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Welwistatin Support Studies: Expansion and Limitation of Aryllead(IV) Coupling Reactions

[Image: see text] Recent support studies on the total synthesis of the welwitstatin system are described. The target step involves lead-mediated arylation of sterically demanding aryl groups and carbon acid coupling partners in order to establish the highly congested tetracyclic core structure. Type...

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Bibliographic Details
Main Authors: Xia, Jibo, Brown, Lauren E., Konopelski, Joseph P.
Format: Artigo
Language:Inglês
Published: 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525610/
https://ncbi.nlm.nih.gov/pubmed/17685656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo071156l
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