Identification of Amino Acid Residues in the Catalytic Domain of RNase E Essential for Survival of Escherichia coli: Functional Analysis of DNase I Subdomain

RNase E is an essential Escherichia coli endoribonuclease that plays a major role in the decay and processing of a large fraction of RNAs in the cell. To better understand the molecular mechanisms of RNase E action, we performed a genetic screen for amino acid substitutions in the catalytic domain o...

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Main Authors: Shin, Eunkyoung, Go, Hayoung, Yeom, Ji-Hyun, Won, Miae, Bae, Jeehyeon, Han, Seung Hyun, Han, Kook, Lee, Younghoon, Ha, Nam-Chul, Moore, Christopher J., Sohlberg, Björn, Cohen, Stanley N., Lee, Kangseok
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2516065/
https://ncbi.nlm.nih.gov/pubmed/18660536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.088492
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