Cadmium-Induced Toxicity in Rat Primary Mid-brain Neuroglia Cultures: Role of Oxidative Stress from Microglia

This study examined the role of oxidative stress in neurotoxic effects of cadmium chloride (Cd) in rat primary mid-brain neuron-glia cultures. Cd accumulated in neuron-glia cultures and produced cytotoxicity in a dose-dependent manner, with IC(50) of 2.5μM 24 h after exposure. (3)H-dopamine uptake i...

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Main Authors: Yang, Zhengqin, Yang, Sufen, Qian, Steven Y., Hong, Jau-Shyong, Kadiiska, Maria B., Tennant, Raymond W., Waalkes, Michael P., Liu, Jie
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2507885/
https://ncbi.nlm.nih.gov/pubmed/17483498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfm106
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