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Design considerations in a sib-pair study of linkage for susceptibility loci in cancer

BACKGROUND: Modern approaches to identifying new genes associated with disease allow very fine analysis of associaton and can be performed in population based case-control studies. However, the sibpair design is still valuable because it requires few assumptions other than acceptably high penetrance...

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Bibliografiset tiedot
Päätekijät: Kerber, Richard A, Amos, Christopher I, Yeap, Beow Y, Finkelstein, Dianne M, Thomas, Duncan C
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2008
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488325/
https://ncbi.nlm.nih.gov/pubmed/18616822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-9-64
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