Prolonged, granulocyte–macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha

INTRODUCTION: A surprising feature of the inflammatory infiltrate in rheumatoid arthritis is the accumulation of neutrophils within synovial fluid and at the pannus cartilage boundary. Recent findings suggest that a distinct subset of IL-17-secreting T-helper cells (T(H)17 cells) plays a key role in...

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Hlavní autoři: Parsonage, Greg, Filer, Andrew, Bik, Magdalena, Hardie, Debbie, Lax, Sian, Howlett, Katherine, Church, Leigh D, Raza, Karim, Wong, See-Heng, Trebilcock, Emily, Scheel-Toellner, Dagmar, Salmon, Mike, Lord, Janet M, Buckley, Christopher D
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2453767/
https://ncbi.nlm.nih.gov/pubmed/18433499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2406
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