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Heme Oxygenase-1-derived Carbon Monoxide Induces the Mycobacterium tuberculosis Dormancy Regulon

The mechanisms that allow Mycobacterium tuberculosis (Mtb) to persist in human tissue for decades and to then abruptly cause disease are not clearly understood. Regulatory elements thought to assist Mtb to enter such a state include the heme two-component sensor kinases DosS and DosT and the cognate...

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Bibliographic Details
Main Authors: Kumar, Ashwani, Deshane, Jessy S., Crossman, David K., Bolisetty, Subhashini, Yan, Bo-Shiun, Kramnik, Igor, Agarwal, Anupam, Steyn, Adrie J. C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440631/
https://ncbi.nlm.nih.gov/pubmed/18400743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M802274200
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