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Plasmodium falciparum antigenic variation. Mapping mosaic var gene sequences onto a network of shared, highly polymorphic sequence blocks

Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a potentially important family of immune targets, encoded by an extremely diverse gene family called var. Understanding of the genetic organization of var genes is hampered by sequence mosaicism that results from a long history of non-...

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Detalhes bibliográficos
Main Authors: Bull, Peter C, Buckee, Caroline O, Kyes, Sue, Kortok, Moses M, Thathy, Vandana, Guyah, Bernard, Stoute, José A, Newbold, Chris I, Marsh, Kevin
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440560/
https://ncbi.nlm.nih.gov/pubmed/18433451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2008.06248.x
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