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Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes

Background and purpose: A prostamide analogue, bimatoprost, has been shown to be effective in reducing intraocular pressure, but its precise mechanism of action remains unclear. Hence, to elucidate the molecular mechanisms of this effect of bimatoprost, we focused on pharmacologically characterizing...

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Main Authors: Liang, Y, Woodward, D F, Guzman, V M, Li, C, Scott, D F, Wang, J W, Wheeler, L A, Garst, M E, Landsverk, K, Sachs, G, Krauss, A H-P, Cornell, C, Martos, J, Pettit, S, Fliri, H
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440084/
https://ncbi.nlm.nih.gov/pubmed/18587449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.142
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