Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes

Background and purpose: A prostamide analogue, bimatoprost, has been shown to be effective in reducing intraocular pressure, but its precise mechanism of action remains unclear. Hence, to elucidate the molecular mechanisms of this effect of bimatoprost, we focused on pharmacologically characterizing...

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Bibliographic Details
Main Authors: Liang, Y, Woodward, D F, Guzman, V M, Li, C, Scott, D F, Wang, J W, Wheeler, L A, Garst, M E, Landsverk, K, Sachs, G, Krauss, A H-P, Cornell, C, Martos, J, Pettit, S, Fliri, H
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2008
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2440084/
https://ncbi.nlm.nih.gov/pubmed/18587449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.142
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