Resveratrol protects against arsenic trioxide-induced cardiotoxicity in vitro and in vivo

BACKGROUND AND PURPOSE: The clinical use of arsenic trioxide (As(2)O(3)), a potent antineoplastic agent, is limited by its severe cardiotoxic effects. QT interval prolongation and apoptosis have been implicated in the cardiotoxicity of As(2)O(3). The present study was designed to evaluate the effect...

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Главные авторы: Zhao, X-Y, Li, G-Y, Liu, Y, Chai, L-M, Chen, J-X, Zhang, Y, Du, Z-M, Lu, Y-J, Yang, B-F
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2008
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Research Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438979/
https://ncbi.nlm.nih.gov/pubmed/18332854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.81
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