C-C Chemokine Receptor 5 on Pulmonary Fibrocytes Facilitates Migration and Promotes Metastasis via Matrix Metalloproteinase 9

Previously, our group has used a B16-F10 melanoma model to show that C-C chemokine receptor 5 (CCR5) knockout (CCR5(−/−)) mice form fewer pulmonary metastases than wild-type mice. This advantage can be eliminated by injecting CCR5(−/−) mice with wild-type pulmonary mesenchymal cells before tumor inj...

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Bibliographische Detailangaben
Hauptverfasser: van Deventer, Hendrik W., Wu, Qing Ping, Bergstralh, Daniel T., Davis, Beckley K., O'Connor, Brian P., Ting, Jenny P.-Y., Serody, Jonathan S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2008
Schlagworte:
Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438302/
https://ncbi.nlm.nih.gov/pubmed/18535183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2008.070732
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