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Transforming function of the LSM1 oncogene in human breast cancers with the 8p11−12 amplicon

Amplification of the 8p11−12 region occurs in 15−20% of breast cancers, but the driving oncogene at this locus has yet to be definitively identified. We mapped the 8p11−12 amplicon in breast cancer cell lines and primary human breast cancers and identified the candidate oncogene LSM1 based on increa...

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Hlavní autoři: Streicher, KL, Yang, ZQ, Draghici, S, Ethier, SP
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435249/
https://ncbi.nlm.nih.gov/pubmed/17001308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1210002
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