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Sir2 Silences Gene Transcription by Targeting the Transition between RNA Polymerase II Initiation and Elongation
It is well accepted that for transcriptional silencing in budding yeast, the evolutionarily conserved lysine deacetylase Sir2, in concert with its partner proteins Sir3 and Sir4, establishes a chromatin structure that prevents RNA polymerase II (Pol II) transcription. However, the mechanism of repre...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2423133/ https://ncbi.nlm.nih.gov/pubmed/18391020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00019-08 |
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