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Investigating the complex genetic architecture of ankle-brachial index, a measure of peripheral arterial disease, in non-Hispanic whites

BACKGROUND: Atherosclerotic peripheral arterial disease (PAD) affects 8–10 million people in the United States and is associated with a marked impairment in quality of life and an increased risk of cardiovascular events. Noninvasive assessment of PAD is performed by measuring the ankle-brachial inde...

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Bibliographic Details
Main Authors: Kardia, Sharon LR, Greene, M Todd, Boerwinkle, Eric, Turner, Stephen T, Kullo, Iftikhar J
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2412898/
https://ncbi.nlm.nih.gov/pubmed/18482449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-1-16
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