Mutations in the VP1 coding region of polyomavirus determine differentiating stage specificity.

Polyomavirus mutants capable of replicating in undifferentiated murine C2 myoblasts were selected and characterized. These mutants grow normally in 3T6 mouse fibroblast cells, and they do not complement the wild-type virus in coinfection experiments of C2 myoblasts. Of 12 isolates, 10 possess duplic...

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Bibliographic Details
Main Authors: Ricci, L, Maione, R, Passananti, C, Felsani, A, Amati, P
Format: Artigo
Language:Inglês
Published: 1992
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC240404/
https://ncbi.nlm.nih.gov/pubmed/1331516
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