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Sirtuins: a conserved key unlocking AceCS activity

Bacterial acetyl-coenzyme A (acetyl-CoA) synthetase (AceCS), an evolutionarily conserved enzyme that converts acetate to acetyl-CoA, is activated by sirtuin-mediated deacetylation. Two recent studies show that this mechanism of regulation is also crucial for mammalian AceCS activity, indicating that...

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Bibliografiska uppgifter
Huvudupphovsmän: North, Brian J., Sinclair, David A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2006
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396790/
https://ncbi.nlm.nih.gov/pubmed/17141505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2006.11.002
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