Prevalence of Leukoencephalopathy in Children Treated for Acute Lymphoblastic Leukemia with High-Dose Methotrexate

BACKGROUND AND PURPOSE: An effective treatment for acute lymphoblastic leukemia (ALL), intravenous (IV) methotrexate (MTX) has a notable toxic effect on the CNS, with leukoencephalopathy (LE) being the most common form. The purpose of this study was to use objective quantitative MR imaging to prospe...

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Главные авторы: Reddick, Wilburn E., Glass, John O., Helton, Kathleen J., Langston, James W., Xiong, Xiaoping, Wu, Shengjie, Pui, Ching-Hon
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Neuroradiology 2005
Предметы:
Pediatrics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2396789/
https://ncbi.nlm.nih.gov/pubmed/15891195
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