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Hypoxic erythrocytes spark lung leukocyte adhesion
Erythrocytes are generally expected to passively transit microvascular beds, carrying oxygen but not delivering ROS. In contrast, Kiefmann and colleagues report in this issue of Blood that, in hypoxic lungs, erythrocytes release ROS, activate endothelium, and trigger leukocyte accumulation.
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2384117/ https://ncbi.nlm.nih.gov/pubmed/18467598 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-140947 |
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