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Pharmacokinetic characteristics and anticancer effects of 5-Fluorouracil loaded nanoparticles

BACKGROUND: It is expected that prolonged circulation of anticancer drugs will increase their anticancer activity while decreasing their toxic side effects. The purpose of this study was to prepare 5-fluorouracil (5-FU) loaded block copolymers, with poly(γ-benzyl-L-glutamate) (PBLG) as the hydrophob...

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Detalhes bibliográficos
Main Authors: Li, Su, Wang, Anxun, Jiang, Wenqi, Guan, Zhongzhen
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375900/
https://ncbi.nlm.nih.gov/pubmed/18412945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-8-103
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