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Phosphatidylinositol-4,5-bisphosphate (PIP(2)) regulation of strong inward rectifier Kir2.1 channels: multilevel positive cooperativity
Inwardly rectifying potassium (Kir) channels are gated by the interaction of their cytoplasmic regions with membrane-bound phosphatidylinositol-4,5-bisphosphate (PIP(2)). In the present study, we examined how PIP(2) interaction regulates channel availability and channel openings to various subconduc...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Blackwell Science Inc
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2375719/ https://ncbi.nlm.nih.gov/pubmed/18276733 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2007.147868 |
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