Cyclin A is a prognostic indicator in early stage breast cancer with and without tamoxifen treatment

Overexpression of G1-S regulators cyclin D1 or cyclin A is frequently observed in breast cancer and is also to result in ligand-independent activation of oestrogen receptor in vitro. This might therefore, provide a mechanism for failure of tamoxifen treatment. We examined by immunohistochemical stai...

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Bibliographic Details
Main Authors: Michalides, R, van Tinteren, H, Balkenende, A, Vermorken, J B, Benraadt, J, Huldij, J, van Diest, P
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2002
Subjects:
Molecular and Cellular Pathology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2375223/
https://ncbi.nlm.nih.gov/pubmed/11875707
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600072
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