Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients

INTRODUCTION: Efforts are ongoing to determine the significance of unclassified variants (UVs) in the breast cancer susceptibility genes BRCA1/BRCA2, but no study has systematically assessed whether women carrying the suspected deleterious UVs have characteristics commonly seen among women carrying...

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Detalhes bibliográficos
Main Authors: Lee, Eunjung, McKean-Cowdin, Roberta, Ma, Huiyan, Chen, Zhengjia, Van Den Berg, David, Henderson, Brian E, Bernstein, Leslie, Ursin, Giske
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374975/
https://ncbi.nlm.nih.gov/pubmed/18284688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr1865
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