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Concentrations of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours

Patients treated with tamoxifen (TAM) for primary breast cancer often manifest de novo or acquired resistance, possibly through changes in drug metabolism. Using solid-phase extraction methods and reversed-phase high-performance liquid chromatography separations, levels of TAM and metabolites 4-hydr...

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Bibliografske podrobnosti
Main Authors: MacCallum, J, Cummings, J, Dixon, J M, Miller, W R
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2000
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374506/
https://ncbi.nlm.nih.gov/pubmed/10817496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1120
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