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Concentrations of tamoxifen and its major metabolites in hormone responsive and resistant breast tumours

Patients treated with tamoxifen (TAM) for primary breast cancer often manifest de novo or acquired resistance, possibly through changes in drug metabolism. Using solid-phase extraction methods and reversed-phase high-performance liquid chromatography separations, levels of TAM and metabolites 4-hydr...

詳細記述

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書誌詳細
主要な著者: MacCallum, J, Cummings, J, Dixon, J M, Miller, W R
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2000
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2374506/
https://ncbi.nlm.nih.gov/pubmed/10817496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1120
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