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Synergistic Effects of Hypofibrinolysis and Genetic and Acquired Risk Factors on the Risk of a First Venous Thrombosis

BACKGROUND: Previously, we demonstrated that hypofibrinolysis, a decreased capacity to dissolve a blood clot as measured with an overall clot lysis assay, increases the risk of venous thrombosis. Here, we investigated the combined effect of hypofibrinolysis with established risk factors associated w...

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Autori principali: Meltzer, Mirjam E, Lisman, Ton, Doggen, Carine J. M, de Groot, Philip G, Rosendaal, Frits R
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365975/
https://ncbi.nlm.nih.gov/pubmed/18462012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0050097
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