Preserved CD4(+) Central Memory T Cells and Survival in Vaccinated SIV-Challenged Monkeys

Vaccine-induced cellular immunity controls virus replication in simian immunodeficiency virus (SIV)–infected monkeys only transiently, leading to the question of whether such vaccines for AIDS will be effective. We immunized monkeys with plasmid DNA and replication-defective adenoviral vectors encod...

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Main Authors: Letvin, Norman L., Mascola, John R., Sun, Yue, Gorgone, Darci A., Buzby, Adam P., Xu, Ling, Yang, Zhi-yong, Chakrabarti, Bimal, Rao, Srinivas S., Schmitz, Jörn E., Montefiori, David C., Barker, Brianne R., Bookstein, Fred L., Nabel, Gary J.
Format: Artigo
Jezik:Inglês
Izdano: 2006
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365913/
https://ncbi.nlm.nih.gov/pubmed/16763152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1124226
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