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Evaluation of E1A Double Mutant Oncolytic Adenovectors in Anti-Glioma Gene Therapy

Malignant glioma, in particular glioblastoma multiforme (GBM), represents one of the most devastating cancers currently known and existing treatment regimens do little to change patient prognosis. Conditionally replicating adenoviral vectors (CRAds) represent attractive experimental anti-cancer agen...

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Main Authors: Ulasov, Ilya V., Tyler, Matthew A., Rivera, Angel A., Nettelbeck, Dirk M., Douglas, Joanne T., Lesniak, Maciej S.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365750/
https://ncbi.nlm.nih.gov/pubmed/18649343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jmv.00000
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