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Combretastatin-A4 disrupts neovascular development in non-neoplastic tissue
Combretastatin-A4 phosphate (cis -CA-4) is a tubulin-binding agent currently undergoing clinical trials as an anti-tumour drug. We have investigated whether CA-4 functions as a tumour-specific anti-vascular agent using the hyperplastic thyroid as a novel in vivo model of neovascularization. CA-4 eli...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2363811/ https://ncbi.nlm.nih.gov/pubmed/11259100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1054/bjoc.2000.1653 |
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