HER2 expression as a potential marker for response to therapy targeted to the EGFR

Since human epidermal growth factor receptor 2 (HER2) is known to participate with the epidermal growth factor receptor (EGFR) in mitogenic signalling, we hypothesised that HER2 overexpression might indicate responsiveness to EGFR targeted therapies. MCF7 breast cancer cells transfected with the HER...

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Библиографические подробности
Главные авторы: Emlet, D R, Schwartz, R, Brown, K A, Pollice, A A, Smith, C A, Shackney, S E
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2006
Предметы:
Translational Therapeutics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361260/
https://ncbi.nlm.nih.gov/pubmed/16622439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603078
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