Polymorphisms of genes coding for insulin-like growth factor 1 and its major binding proteins, circulating levels of IGF-I and IGFBP-3 and breast cancer risk: results from the EPIC study

Insulin-like growth factor I (IGF-I) stimulates cell proliferation and can enhance the development of tumours in different organs. Epidemiological studies have shown that an elevated level of circulating IGF-I is associated with increased risk of breast cancer, as well as of other cancers. Most of c...

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Main Authors: Canzian, F, McKay, J D, Cleveland, R J, Dossus, L, Biessy, C, Rinaldi, S, Landi, S, Boillot, C, Monnier, S, Chajès, V, Clavel-Chapelon, F, Téhard, B, Chang-Claude, J, Linseisen, J, Lahmann, P H, Pischon, T, Trichopoulos, D, Trichopoulou, A, Zilis, D, Palli, D, Tumino, R, Vineis, P, Berrino, F, Bueno-de-Mesquita, H B, van Gils, C H, Peeters, P H M, Pera, G, Ardanaz, E, Chirlaque, M-D, Quirós, J R, Larrañaga, N, Martínez-García, C, Allen, N E, Key, T J, Bingham, S A, Khaw, K-T, Slimani, N, Norat, T, Riboli, E, Kaaks, R
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2006
Subjects:
Genetics and Genomics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361124/
https://ncbi.nlm.nih.gov/pubmed/16404426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6602936
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