Circulating insulin-like growth factor axis and the risk of pancreatic cancer in four prospective cohorts

Insulin-like growth factor (IGF)-I induces growth in pancreatic cancer cells and blockade of the IGF-I receptor has antitumour activity. The association of plasma IGF-I and IGF binding protein-3 (IGFBP-3) with pancreatic cancer risk has been investigated in two small studies, with conflicting result...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wolpin, B M, Michaud, D S, Giovannucci, E L, Schernhammer, E S, Stampfer, M J, Manson, J E, Cochrane, B B, Rohan, T E, Ma, J, Pollak, M N, Fuchs, C S
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Molecular Diagnostics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359655/
https://ncbi.nlm.nih.gov/pubmed/17533398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603826
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