Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid

BACKGROUND: Inflammation is associated with Aβ pathology in Alzheimer's disease (AD) and transgenic AD models. Previously, it has been demonstrated that chronic stimulation of the immune response induces pro-inflammatory cytokines IL-1β and TNF-α which contribute to neurodegeneration. However,...

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Autori principali: Nichol, Kathryn E, Poon, Wayne W, Parachikova, Anna I, Cribbs, David H, Glabe, Charles G, Cotman, Carl W
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329612/
https://ncbi.nlm.nih.gov/pubmed/18400101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-13
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