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Importance of intrathymic mixed chimerism for the maintenance of skin allograft tolerance across fully allogeneic antigens in mice

In B6 (H-2(b)) mice that had been given, neonatally, 1×10(8) B6AKF1 spleen cells intraperitoneally (i.p.), only a moderate prolongation of donor (AKR:H-2(k)) skin graft survival was observed. In such B6 mice, no mixed lymphocyte reaction (MLR) to AKR could be detected on day 35 (35 days after birth)...

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Autors principals: Eto, M, Kong, Y-Y, Uozumi, J, Naito, S, Nomoto, K
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2326766/
https://ncbi.nlm.nih.gov/pubmed/10233726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2567.1999.00700.x
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