Genetic dissection of thyroid hormone receptor beta: identification of mutations that separate hormone binding and transcriptional activation.

The thyroid hormone receptors (TR) are members of the nuclear receptor family of ligand-mediated transcription factors. The large region of TR that lies C-terminal to its DNA-binding domain subserves functions of ligand binding, dimerization, and transactivation. Little is known regarding the struct...

Full description

Saved in:
Bibliographic Details
Main Authors: Uppaluri, R, Towle, H C
Format: Artigo
Language:Inglês
Published: 1995
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC230374/
https://ncbi.nlm.nih.gov/pubmed/7862143
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items