Compatible osmolytes modulate the response of porcine endothelial cells to hypertonicity and protect them from apoptosis

Porcine pulmonary arterial endothelial cells accumulated myo-inositol and taurine, as well as betaine, during adaptation to hypertonic stress. The cells grew and maintained their normal morphology during culture in hypertonic (0.5 osmol (kg H(2)O)(−1)) medium that contained osmolytes such as betaine...

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Bibliographic Details
Main Authors: Alfieri, Roberta R, Cavazzoni, Andrea, Petronini, Pier Giorgio, Bonelli, Mara A, Caccamo, Alessandro E, Borghetti, Angelo F, Wheeler, Kenneth P
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2002
Subjects:
Research Papers
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290260/
https://ncbi.nlm.nih.gov/pubmed/11956339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.013395
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