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Oxygen uptake on-kinetics in dog gastrocnemius in situ following activation of pyruvate dehydrogenase by dichloroacetate

The aim of the present study was to determine whether the activation of the pyruvate dehydrogenase complex (PDC) by dichloroacetate (DCA) is associated with faster O(2) uptake (V̇(O2)) on-kinetics. V̇(O2) on-kinetics was determined in isolated canine gastrocnemius muscles in situ (n = 6) during the...

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Autores principales: Grassi, Bruno, Hogan, Michael C, Greenhaff, Paul L, Hamann, Jason J, Kelley, Kevin M, Aschenbach, William G, Constantin-Teodosiu, Dumitru, Gladden, L Bruce
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2002
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2290023/
https://ncbi.nlm.nih.gov/pubmed/11773328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2001.012984
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