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Darwinian Evolution on a Chip

Computer control of Darwinian evolution has been demonstrated by propagating a population of RNA enzymes in a microfluidic device. The RNA population was challenged to catalyze the ligation of an oligonucleotide substrate under conditions of progressively lower substrate concentrations. A microchip-...

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Bibliografiske detaljer
Main Authors: Paegel, Brian M, Joyce, Gerald F
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2288630/
https://ncbi.nlm.nih.gov/pubmed/18399721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0060085
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