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Solution structure of APETx2, a specific peptide inhibitor of ASIC3 proton-gated channels
Acid-sensing ion channels (ASIC) are proton-gated sodium channels that have been implicated in pain transduction associated with acidosis in inflamed or ischemic tissues. APETx2, a peptide toxin effector of ASIC3, has been purified from an extract of the sea anemone Anthopleura elegantissima. APETx2...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279311/ https://ncbi.nlm.nih.gov/pubmed/15987885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051378905 |
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