Remodelling of ionic currents in hypertrophied and failing hearts of transgenic mice overexpressing calsequestrin

1. Overexpression of cardiac calsequestrin (CSQ) impairs Ca(2+) signalling in murine myocytes, leading to marked cardiac hypertrophy. Here we report on contractile, histological and electrophysiological changes accompanying the development of cardiac hypertrophy and failure in CSQ-overexpressing mic...

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Autores principales: Knollmann, Björn C, Knollmann-Ritschel, Barbara E C, Weissman, Neil J, Jones, Larry R, Morad, Martin
Formato: Artigo
Lenguaje:Inglês
Publicado: Blackwell Science Inc 2000
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2269956/
https://ncbi.nlm.nih.gov/pubmed/10835049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.2000.t01-1-00483.x
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