Effect of acute hyperglycaemia and/or hyperinsulinaemia on proinflammatory gene expression, cytokine production and neutrophil function in humans

AIMS: Type 2 diabetes is frequently associated with infectious complications. Swift activation of leucocytes is important for an adequate immune response. We determined the selective effects of hyperglycaemia and hyperinsulinaemia on lipopolysaccharide (LPS)-induced proinflammatory gene expression a...

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Detalhes bibliográficos
Main Authors: Stegenga, M E, van der Crabben, S N, Dessing, M C, Pater, J M, van den Pangaart, P S, de Vos, A F, Tanck, M W, Roos, D, Sauerwein, H P, van der Poll, T
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2008
Assuntos:
Original Article: Treatment
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268957/
https://ncbi.nlm.nih.gov/pubmed/18290856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1464-5491.2007.02348.x
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