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Assessing the potential of mutational strategies to elicit new phenotypes in industrial strains

Industrial strains have been traditionally improved by rational approaches and combinatorial methods involving mutagenesis and selection. Recently, other methods have emerged, such as the use of artificial transcription factors and engineering of the native ones. As methods for generating genetic di...

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Detalhes bibliográficos
Main Authors: Klein-Marcuschamer, Daniel, Stephanopoulos, Gregory
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2268134/
https://ncbi.nlm.nih.gov/pubmed/18252819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0712177105
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