Humanized anti-CD4 monoclonal antibody therapy of autoimmune and inflammatory disease

We have investigated the biological and therapeutic properties of a humanized anti-CD4 MoAb, hlgGl-CD4, in patients with refractory psoriasis and rheumatoid arthritis (RA). hIgGl-CD4 is a modulating, non-depleting MoAb, which induced a first-dose reaction in most patients treated. It provided brief...

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Bibliographic Details
Main Authors: ISAACS, J D, BURROWS, N, WING, M, KEOGAN, M T, REBELLO, P R U B, WATTS, R A, PYE, R J, NORRIS, P, HAZELMAN, B L, HALE, G, WALDMANN, H
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 1997
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2265492/
https://ncbi.nlm.nih.gov/pubmed/9367397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.1997.tb08312.x
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