4E10-Resistant Variants in a Human Immunodeficiency Virus Type 1 Subtype C-Infected Individual with an Anti-Membrane-Proximal External Region-Neutralizing Antibody Response

The broadly neutralizing monoclonal antibody (MAb) 4E10 recognizes a linear epitope in the C terminus of the membrane-proximal external region (MPER) of gp41. This epitope is particularly attractive for vaccine design because it is highly conserved among human immunodeficiency virus type 1 (HIV-1) s...

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Bibliographic Details
Main Authors: Gray, Elin S., Moore, Penny L., Bibollet-Ruche, Frederic, Li, Hui, Decker, Julie M., Meyers, Tammy, Shaw, George M., Morris, Lynn
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2008
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2258954/
https://ncbi.nlm.nih.gov/pubmed/18094155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02161-07
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