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Site-directed mutations of human hemoglobin at residue 35β: A residue at the intersection of the α1β1, α1β2, and α1α2 interfaces

Because Tyr35β is located at the convergence of the α1β1, α1β2, and α1α2 interfaces in deoxyhemoglobin, it can be argued that mutations at this position may result in large changes in the functional properties of hemoglobin. However, only small mutation-induced changes in functional and structural p...

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Detalhes bibliográficos
Main Authors: Kavanaugh, Jeffrey S., Weydert, Jamie A., Rogers, Paul H., Arnone, Arthur, Hui, Hilda L., Wierzba, Anita M., Kwiatkowski, Laura D., Paily, Paul, Noble, Robert W., Bruno, Stefano, Mozzarelli, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253201/
https://ncbi.nlm.nih.gov/pubmed/11514675
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