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A general model of G protein-coupled receptor sequences and its application to detect remote homologs

G protein-coupled receptors (GPCRs) constitute a large superfamily involved in various types of signal transduction pathways triggered by hormones, odorants, peptides, proteins, and other types of ligands. The superfamily is so diverse that many members lack sequence similarity, although they all sp...

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Détails bibliographiques
Auteurs principaux: Wistrand, Markus, Käll, Lukas, Sonnhammer, Erik L.L.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249772/
https://ncbi.nlm.nih.gov/pubmed/16452613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051745906
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