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A general model of G protein-coupled receptor sequences and its application to detect remote homologs

G protein-coupled receptors (GPCRs) constitute a large superfamily involved in various types of signal transduction pathways triggered by hormones, odorants, peptides, proteins, and other types of ligands. The superfamily is so diverse that many members lack sequence similarity, although they all sp...

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Detalhes bibliográficos
Main Authors: Wistrand, Markus, Käll, Lukas, Sonnhammer, Erik L.L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2249772/
https://ncbi.nlm.nih.gov/pubmed/16452613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051745906
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