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Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells

Estrogen receptors (ERs), which mediate the proliferative action of estrogens in breast cancer cells, are ligand-dependent transcription factors that regulate expression of their primary target genes through several mechanisms. In addition to direct binding to cognate DNA sequences, ERs can be recru...

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Autors principals: Bourdeau, Véronique, Deschênes, Julie, Laperrière, David, Aid, Malika, White, John H., Mader, Sylvie
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2248750/
https://ncbi.nlm.nih.gov/pubmed/17986456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm945
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