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Bacterial Actin Assembly Requires Toca-1 to Relieve N-WASP Autoinhibition
Actin polymerization in the mammalian cytosol can be locally activated by mechanisms that relieve the autoinhibited state of N-WASP, an initiator of actin assembly, a process that also requires the protein Toca-1. Several pathogenic bacteria, including Shigella, exploit this host feature to infect a...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2234351/ https://ncbi.nlm.nih.gov/pubmed/18191793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2007.10.011 |
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