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Bacterial Actin Assembly Requires Toca-1 to Relieve N-WASP Autoinhibition

Actin polymerization in the mammalian cytosol can be locally activated by mechanisms that relieve the autoinhibited state of N-WASP, an initiator of actin assembly, a process that also requires the protein Toca-1. Several pathogenic bacteria, including Shigella, exploit this host feature to infect a...

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Hlavní autoři: Leung, Yiuka, Ally, Shabeen, Goldberg, Marcia B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234351/
https://ncbi.nlm.nih.gov/pubmed/18191793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2007.10.011
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