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ATP-sensitive K(+) channel activation by calcitonin gene-related peptide and protein kinase A in pig coronary arterial smooth muscle

1. We used patch clamp to study whole-cell K(+) currents activated by calcitonin gene-related peptide (CGRP) in smooth muscle cells freshly dissociated from pig coronary arteries. 2. CGRP (50 nm) activated an inward current at −60 mV in symmetrical 140 mm K(+) that was blocked by glibenclamide (10 μ...

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Main Authors: Wellman, G C, Quayle, J M, Standen, N B
格式: Artigo
語言:Inglês
出版: Blackwell Science Inc 1998
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230768/
https://ncbi.nlm.nih.gov/pubmed/9490826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7793.1998.117bu.x
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